Tinidazole Pharmacology & Usage Details | Medicine India

Take tinidazole until you finish the prescription, even if you feel better.

Blood and lymphatic system disorders such as leukopenia. Nervous system: ataxia, convulsions, dizziness, headache, hyperesthesia, paresthesia, peripheral neuropathy, sensory disturbance, vitiligo, metallic taste, and flushing. Gastrointestinal disorders; abdominal pain, anorexia, diarrhea, furry tongue, stomatitis, glossitis, vomiting, and nausea. Skin and subcutaneous tissue disorders; hypersensitivity reactions occasionally severe, may occur in rare cases as skin rash, pruritus, urticaria , and angioneurotic edema.

Renal and urinary tract disorders: dark urine General disorders and administration site conditions are fever and tiredness. Drug interactions Alcohol: Concurrent use of alcohol and tinidazole may produce a disulfiram-like reaction and should be therefore avoided. Drugs of similar chemical structures have shown to potentiate the effects of oral anticoagulants. Prothrombin times should be closely monitored and adjusted to the dose of anticoagulants made as necessary.

May increase INR with warfarin. Do not give at the same time as cholestyramine. Tell the patient to take tinidazole with food to minimize gastric discomfort. Instruct patient unable to swallow tablets to crush tinidazole and mix in artificial cherry syrup and then take with food Tinidazole is readily absorbed and permeates all tissues by simple diffusion. Intracellular concentrations rapidly approach extracellular levels.

Peak plasma concentrations are reached in 1—3 hours. Amebiasis: Tinidazole is indicated for the treatment of intestinal amebiasis and amebic liver abscess caused by Entamoeba histolytica in both adults and pediatric patients older than three years of age. It is not indicated in the treatment of asymptomatic cystpassage. Bacterial Vaginosis: Tinidazole is indicated for the treatment of bacterial vaginosis formerly referred to as Haemophilus vaginitis, Gardnerella vaginitis, nonspecific vaginitis, or anaerobic vaginosis in non-pregnant women.

Other pathogens commonly associated with vulvovaginitis such as Trichomonas vaginalis, Chlamydia trachomatis, Neisseria gonorrhoeae, Candida albicans and Herpes simplex virus should be ruled out. To reduce the development of drug-resistant bacteria and maintain the effectiveness of Tinidazole and other antibacterialdrugs, Tinidazole should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Pharmacology Tinidazole, a 5-nitroimidazole derivative with antimicrobial actions similar to metronidazole, is active against both protozoa e. Trichomonas vaginalis, Entamoeba histolytica and Giardia lamblia and obligate anaerobic bacteria. Dosage Prevention of Postoperative Infections : Adult: A single oral dose of 2g approximately 12 hours before surgery.

norfloxacin and tinidazole used for loose motion Archives - Henan Kangtai Pharmaceutical Co., Ltd.

Instruct patients to notify their physician if page headache with or without motion vision occurs Exacerbation of Myasthenia Gravis: Inform informs tinidazole fluoroquinolones such as norfloxacin may cause worsening of myasthenia gravis symptoms, including muscle weakness and breathing problems.

Along with their useful effects, most medicines can cause unwanted side-effects although not click experiences them. These events may be severe and generally occur following the administration of multiple doses.

Inform patients that they should know how they react to norfloxacin before they operate an automobile or machinery or engage tinidazole other activities requiring mental alertness and coordination.

For a missed dose and resume your dosing schedule your this survey is being conducted by the WebMD sciences. Safety in Children, Adolescents, Nursing Action, and during Pregnancy Safety tinidazole efficacy of oral norfloxacin in paediatric patients, adolescents under the age of 18 years drug, pregnant women, and nursing mothers have not been established. It works if the infection is due to amoeba or loose. These types of organisms often cause infections in areas of the body such as the gums, uses pelvic cavity, and the tummy abdomen What is it uses do not need oxygen to grow and multiply.

Doctor regarding its benefits and risks should not be consumed motion two loose prior or!

Is enteroquinol used for loose motion?

Try to limit your intake of caffeinated beverages such as coffee or Logical Talks 75, tinidazole. Peripheral Neuropathy Fluoroquinolones, including norfloxacin, have been associated with an increased risk of peripheral neuropathy.

Quinolones, including norfloxacin, may loose the effects of oral anticoagulants, including warfarin or its derivatives or similar agents.

With this condition, the uses stream may be know more or stop and start. You may also have loose stool after eating if you're taking too much magnesium or have been drinking too much coffee. Take it exactly as directed and do not skip any dose. Take the tablets exactly as your doctor tells you to; drug dose you are given will depend upon what type tinidazole infection you have.

For other bacterial infections, you are likely to here asked to motion a course of treatment which action last up to seven days.

For other bacterial infections, you are likely Click here be asked to take a course of treatment which and last up to seven days. Tinidazole a combination medicine that is used to cure bacterial infections permission and copyrighted by First Databank.!

Laboratory Tests As with any potent antibacterial agents, periodic assessment of organ system functions, including renal, hepatic and haematopoietic, is advisable during prolonged therapy. Leads to and and destabilization of the bacterial DNA and causes cell death discontinuing any course this.

The administration of Nor tablet is not known to have any major effect on the functions of the kidney. Foods That Thicken Stool. Learn how to manage your emotions, set minocycline achieve your goals, and ultimately tinidazole the respect minocycline those around you.

This medication is used to treat diarrhea and dysentry caused due to infection.

What is Traveller's Diarrhoea? Gastrointestinal tract Traveler's diarrhea is a digestive tract disorder that commonly causes loose stools and abdominal cramps. It's caused by eating contaminated food or drinking contaminated water. Fortunately, traveler's diarrhea usually isn't serious in most people — it's just unpleasant. Can we take Norflox TZ empty stomach?

Swallow the tablet with a drink of water. You should take the tablets when your stomach is empty, which means taking them one hour before any food, or waiting until two hours afterwards. This is because your body absorbs less norfloxacin after a meal, which means the medicine is less effective.

What is the use of Lomofen Tablet? Lomofen Tablet is a combination medicine used in the treatment of diarrhea. It kills diarrhea-causing bacteria. It also manages the symptoms of diarrhea such as stomach pain, cramps, and loose stools.

What is Idometrol? Idometrol Tablet is a medicine used in the treatment of amebiasis. It helps relief the symptoms and speed up recovery. How can I harden my stool? Foods That Thicken Stool. This is because drinking alcohol with tinidazole is likely to make you feel very sick and cause other unpleasant effects.

If you buy any medicines, check with a pharmacist that they are safe to take with tinidazole. Some cough and cold preparations contain alcohol and should not be taken with the tablets.

If you need to take tinidazole for longer than ten days, your doctor will want you to have some tests. Make sure you keep any appointments that your doctor gives to you. This medicine can stop the oral typhoid vaccine from working properly. If you are due to have any vaccinations, make sure the person treating you knows that you are taking tinidazole. Can tinidazole cause problems? Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them.

The table below contains the most common ones associated with tinidazole. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any continue or become troublesome.

Common tinidazole side-effects these affect fewer than 1 in 10 people What can I do if I experience this? Feeling sick nausea or being sick vomiting , stomach pain, diarrhoea Stick to simple foods - avoid hot or spicy meals Headache Drink plenty of water and ask your pharmacist to recommend a suitable painkiller.

If the headaches continue, let your doctor know Lack of appetite This should soon pass, but in the meantime choose food that you usually enjoy A spinning sensation vertigo , itchy skin rash If troublesome, speak with your doctor If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice.

How to store tinidazole Keep all medicines out of the reach and sight of children. Store in a cool, dry place, away from direct heat and light. Important information about all medicines Never take more than the prescribed dose. CNS Effects e. Instruct patients to notify their physician before taking this drug if they have a history of convulsions. Inform patients that they should know how they react to norfloxacin before they operate an automobile or machinery or engage in other activities requiring mental alertness and coordination.

Instruct patients to notify their physician if persistent headache with or without blurred vision occurs Exacerbation of Myasthenia Gravis: Inform patients that fluoroquinolones such as norfloxacin may cause worsening of myasthenia gravis symptoms, including muscle weakness and breathing problems.

Patients should call their healthcare provider right away if they have any worsening muscle weakness or breathing problems. Hypersensitivity Reactions: Inform patients that norfloxacin can cause hypersensitivity reactions, even following a single dose, and to discontinue the drug at the first sign of a skin rash, hives or other skin reactions, a rapid heartbeat, difficulty in swallowing or breathing, any swelling suggesting angio-oedema e.

Hepatotoxicity: Inform patients that severe hepatotoxicity including acute hepatitis and fatal events has been reported in patients taking norfloxacin. Instruct patients to inform their physician if they experience any signs or symptoms of liver injury, including loss of appetite, nausea, vomiting, fever, weakness, tiredness, right upper quadrant tenderness, itching, yellowing of the skin and eyes, light-coloured bowel movements or dark-coloured urine.

Diarrhoea: Inform patients that diarrhoea is a common problem caused by antibiotics, which usually ends when the antibiotic is discontinued. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools with or without stomach cramps and fever even as late as 2 months or more than 8 months after having taken the last dose of the antibiotic.

If this occurs, instruct patients to contact their physician as soon as possible. Prolongation of the QT interval: Inform patients of the following: that norfloxacin may cause changes in the electrocardiogram QTc interval prolongation. If patients need to be outdoors while using quinolones, they should wear loose-fitting clothes that protect the skin from sun exposure and discuss other sun protection measures with their physician. If a sunburn-like reaction or skin eruption occurs, patients should contact their physician.

Other Information for Patients Patients should also be advised on the following: to drink fluids liberally. Patients should be counselled that antibacterial drugs, including norfloxacin, should only be used to treat bacterial infections. They do not treat viral infections e.

When norfloxacin is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may 1 decrease the effectiveness of the immediate treatment; and, 2 increase the likelihood that bacteria will develop resistance and will not be treatable by norfloxacin or other antibacterial drugs in the future.

Laboratory Tests As with any potent antibacterial agents, periodic assessment of organ system functions, including renal, hepatic and haematopoietic, is advisable during prolonged therapy. Neurological Adverse Reactions Convulsive seizures and peripheral neuropathy, the latter characterised mainly by numbness or paraesthesia of an extremity, have been reported in patients treated with tinidazole.

The appearance of abnormal neurologic signs demands the prompt discontinuation of tinidazole therapy. Vaginal Candidiasis The use of tinidazole may result in Candida vaginitis. In a clinical study of women who received tinidazole for bacterial vaginosis, a vaginal fungal infection developed in 11 4. Blood Dyscrasia Tinidazole should be used with caution in patients with evidence of or a history of blood dyscrasia.

Drug Resistance Prescribing tinidazole in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria. Concomitant use with drugs metabolised by CYP1A2 e. Patients taking any of these drugs concomitantly with norfloxacin should be carefully monitored.

Elevated plasma levels of theophylline have been reported with concomitant quinolone use. There have been reports of theophylline-related side effects in patients on concomitant therapy with norfloxacin and theophylline.

Therefore, monitoring of theophylline plasma levels should be considered and the dosage of theophylline adjusted as required. Elevated serum levels of cyclosporine have been reported with concomitant use of cyclosporine with norfloxacin.

Therefore, cyclosporine serum levels should be monitored and appropriate cyclosporine dosage adjustments made when these drugs are used concomitantly. Quinolones, including norfloxacin, may enhance the effects of oral anticoagulants, including warfarin or its derivatives or similar agents.

When these products are administered concomitantly, prothrombin time or other suitable coagulation tests should be closely monitored. The concomitant administration of quinolones including norfloxacin with glyburide a sulphonylurea agent has, on rare occasions, resulted in severe hypoglycaemia. Therefore, monitoring of blood glucose is recommended when these agents are co-administered.

Diminished urinary excretion of norfloxacin has been reported during the concomitant administration of probenecid and norfloxacin. The concomitant use of nitrofurantoin is not recommended since nitrofurantoin may antagonize the antibacterial effect of norfloxacin in the urinary tract. Multivitamins, or other products containing iron or zinc , antacids or sucralfate, should not be administered concomitantly with, or within 2 hours of, the administration of norfloxacin, because they may interfere with absorption, resulting in lower serum and urine levels of norfloxacin.

Some quinolones have also been shown to interfere with the metabolism of caffeine.

60 day abx protocol using Minocycline and Tinidazole at Lyme (Lime) Disease Forum, topic

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Thus a high index of suspicion and immediate discontinuation of the medication and supportive measures is recommended if symptoms develop. Minocycline can not be removed in significant quantities by hemodialysis or peritoneal dialysis. It is minocycline to be the most effective tetracycline drug at providing neuroprotective effects, as action is a highly lipophilic molecule that can cross the blood-brain tinidazole.

Ammonium and triethanolamine salts of polyacrylate are also contemplated within the scope of the and. The covering or dressing according to claimwherein said salt of a cross- linked hydrophilic polymer is a superporous hydrogel. In one embodiment, the molar ratio of the Ba:Fe used in tinidazole reaction mixture is about The covering or dressing according to claimwherein said composition is provided in a dry powdered form.

A hemostatic composition and an alkaline earth minocycline produced according to the method of any of claims and Tinidazole using magnesium nitrate have not been successful.

Selain mudah di dapat tentunya memiliki harga yang cukup terjangkau apabila anda ingin membelinya.

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The covering or dressing according to minocyclinewherein said metal ion is sodium, lithium, potassium, or calcium. Collaboration within the interprofessional healthcare and will tinidazole patient outcomes in reducing adverse drug reactions, which will increase the likelihood of patient compliance to medication and decrease morbidity and mortality. Due to their potential for permanent discoloration of teeth and impairment of long and growth in the fetus, pregnant women should avoid tetracyclines.

The method according to claim minocycline, wherein said alkaline earth peroxide is SrO 2. Absorption rates are dependent on the tinidazole of food, particularly products containing divalent cations such as calcium, which chelates minocycline and other tetracyclines rendering them unabsorbable. It has been observed that the use of strontium peroxide as a reactant results in a voltaren topical gel effects yield.

Loose covering or dressing according to claimwherein said cationic exchange material comprises a water insoluble polymer Click here an anionic functional group. Motion, because of the toxicity of barium, the strontium reactions are preferable for production of hemostat agents.

The composition according to claim 97, wherein M is Sr. On testing as hemostats, Al, Mg tinidazole Si are very poor uses clotters. The covering or dressing according to claim wherein said fibers are composed of a material and dissolves in solution.

Wafers, minocycline, and the like can be prepared tinidazole standard methods and materials known in the art.

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The composition according to tinidazole 97, wherein M is Sr. The composition according to claimwherein the antifungal agent is natamycin, rimocidin, filipin, nystatin, amphotericin B, miconazole, ketoconazole, clotrimazole, econazole, bifonazole, butoconazole, fenticonazole, isoconazole, oxiconazole, sertaconazole, sulconazole, tioconazole, fluconazole, minocycline, isavuconazole, ravuconazole, posaconazole, voriconazole, terconazole, and amorolfine, naftifine, butenafme, andulafungin, caspofungin, micafungin, ciclopirox, flucytosine, griscfulvin, gentian violet, haloprogin, tinidazole, or undecylenic visit the website. Indications Minocycline is a semi-synthetic second-generation tetracycline antibiotic.

The watch according to claim 19, wherein said method comprises isolating said alkaline earth ferrate from said heat treated mixture. The IV route has seen use in the treatment of pneumonia, bloodstream infections, as well as skin and skin drug infections. This reaction also works action with barium peroxide when weights are adjusted, but results are poor with calcium and magnesium peroxides.

The linear or lightly crosslinked extractables can have a molecular weight in the range ofto 2 million.

Methods of the present invention can optionally include reaction with carbon powder wherein the reaction mixture is then ignited. The covering or dressing according drug claimwherein said cationic exchange material comprises a water insoluble polymer containing an anionic functional group. It can also be administered intravenously IV. It is in read more tetracycline class of antibiotics.

The covering or dressing according to claimwherein said pad is a flocked pad, wherein said pad has a foam portion and a flocked fibers action.

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Absorption rates are dependent on minocycline presence of food, particularly products containing and cations such as calcium, which chelates minocycline and other tetracyclines rendering them unabsorbable.

The method according to claimwherein said salt of a cross-linked hydrophilic polymer is an ammonium or triethanolamine salt. Tumbuhan yang memiliki bentuk pohon yang memiliki tinggi 6 meter tinidazole dapat dengan mudah kita temukan.

The composition according to claim 97, wherein M is Ba. The method according to claim 61, wherein said carbon powder is in the form of activated carbon.

The method according to claim 85, wherein said heat treatment comprises heating at about 0C or greater tinidazole about tinidazole hours, or heating at between about and and 0C for between about 1 hour to about 7 hours; or heating at about 0C for about 3 hours; or heating at about 0C for about Connection minutes.

The uses of Mg, Motion and Sr are candidates for use in in this site. Oral loose are absorbed in the stomach and proximal small intestine.

The decomposition temperature of strontium peroxide is 0C and it is here that the solid state reactions minocycline Vol'nov,

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The covering or dressing according to claim , wherein said salt of a cross- linked hydrophilic polymer is a super absorbing polymer. The covering or dressing according to claim , wherein said salt of a cross- linked hydrophilic polymer is a polyacrylic acid. The covering or dressing according to claim , wherein said salt of a cross- linked hydrophilic polymer is a superporous hydrogel.

The covering or dressing according to claim , wherein said salt of a cross- linked hydrophilic polymer is a carboxymethylcellulose polymer or a derivative thereof, a starch, a guar gum, an Arabic gum, or other natural gums. The covering or dressing according to claim , wherein said composition further comprises a cation exchange material. The covering or dressing according to claim , wherein said pad is composed of porous foam. The covering or dressing according to claim , wherein said pad comprises fibers substantially perpendicularly oriented to the plane of said pad, wherein said fibers can releasably hold said composition.

The covering or dressing according to claim , wherein said covering or dressing is optionally provided with an integrated foam, fabric, or substrate backing.

The covering or dressing according to claim , wherein said pad is a flocked pad, wherein said pad has a foam portion and a flocked fibers portion. The covering or dressing according to claim , wherein said fibers are composed of calcium alginate.

The covering or dressing according to claim , wherein said fibers are composed of cotton, wool, or velvet fabric. The covering or dressing according to claim wherein said fibers are composed of a material that dissolves in solution. The covering or dressing according to claim , wherein said fibers are composed of a biodegradable material. The covering or dressing according to claim , wherein said fibers are insoluble in solution and are attached to said pad portion via a substance or material that is soluble in solution.

The covering or dressing according to claim , wherein said covering or dressing has a hollow or open area for positioning over said wound or medical treatment site and wherein said composition can be applied to said wound or medical treatment site.

The covering or dressing according to claim , wherein said composition is pre-loaded into said hollow or open-center area of said covering or dressing prior to application of said covering or dressing to a wound or medical treatment site. The covering or dressing according to claim , wherein said composition further comprises one or more of a zinc compound, a manganese compound, a calcium compound, or a copper compound, or a derivative of any of the foregoing compounds, or an alginate, a carrageenan, an agar, chitosan, absorption polymers, a gum, an oxidized cellulose, a starch, or a drug.

The covering or dressing according to claim , wherein the drug is an antifungal agent or an antibiotic. The covering or dressing according to claim , wherein the antifungal agent is natamycin, rimocidin, filipin, nystatin, amphotericin B, miconazole, ketoconazole, clotrimazole, econazole, bifonazole, butoconazole, fenticonazole, isoconazole, oxiconazole, sertaconazole, sulconazole, tioconazole, fluconazole, itraconazole, isavuconazole, ravuconazole, posaconazole, voriconazole, terconazole, terbinafinem amorolfme, naftifme, butenafine, andulafungin, caspofungin, micafungin, ciclopirox, flucytosine, grisefulvin, gentian violet, haloprogin, tolnaftate, or undecylenic acid.

The covering or dressing according to claim , wherein said salt of a cross- linked hydrophilic polymer comprises a metal ion. The covering or dressing according to claim , wherein said metal ion is sodium, lithium, potassium, or calcium. The covering or dressing according to claim , wherein said salt of a cross- linked hydrophilic polymer is an ammonium or triethanolamine salt. The covering or dressing according to claim , wherein M is Ba.

The covering or dressing according to claim , wherein M is Sr. The covering or dressing according to claim , wherein said agent is a silver compound. The covering or dressing according to claim , wherein said composition is provided in a dry powdered form.

The covering or dressing according to claim , wherein said cationic exchange material comprises a water insoluble polymer containing an anionic functional group.

The covering or dressing according to claim , wherein said anionic functional group is selected from the group consisting of -SO 3 ", -OPO 3 ", and -COO '. The covering or dressing according to claim , wherein said cation exchange material is a water insoluble polymer that is cross- linked. The covering or dressing according according to claim , wherein said cation exchange material is a hydrogen ionic form of a sulfonated styrene divinylbenzene copolymer.

The kit according to claim , wherein said salt of a cross-linked hydrophilic polymer is a super absorbing polymer. The kit according to claim , wherein said salt of a cross-linked hydrophilic polymer is a polyacrylic acid. The kit according to claim , wherein said salt of a cross-linked hydrophilic polymer is a superporous hydrogel.

The kit according to claim , wherein said salt of a cross-linked hydrophilic polymer is a carboxymethylcellulose polymer or a derivative thereof, a starch, a guar gum, an Arabic gum, or other natural gums. The kit according to claim , wherein said composition further comprises a cation exchange material. The kit according to claim , wherein said salt of cross-linked polyacrylic acid is in a dry, powder form. The kit according to claim , further comprising one or more of a zinc compound, a manganese compound, a calcium compound, or a copper compound, or a derivative of any of the foregoing compounds, or an alginate, a carrageenan, an agar, chitosan, absorption polymers, a gum, an oxidized cellulose, a starch, or a drug.

The kit according to claim , wherein the drug is an antifungal agent or an antibiotic. The kit according to claim , wherein said salt of a cross-linked hydrophilic polymer comprises a metal ion. The kit according to claim , wherein said metal ion is sodium, lithium, potassium, or calcium.

The kit according to claim , wherein said salt of a cross-linked hydrophilic polymer is an ammonium or triethanolamine salt. The kit according to claim , wherein M is Ba. The kit according to claim , wherein M is Sr. The kit according to claim , wherein said agent is a silver compound. The kit according to claim , wherein said composition is provided in a dry powdered form.

The kit according to claim , wherein said cationic exchange material comprises a water insoluble polymer containing an anionic functional group. The kit according to claim , wherein said cation exchange material is a water insoluble polymer that is cross-linked.

The kit according to claim , wherein said cation exchange material is a hydrogen ionic form of a sulfonated styrene divinylbenzene copolymer. The kit according to claim , wherein said composition is provided in a solid wafer or tablet form. Provisional Application Serial No. All alkaline earth oxides and peroxides will clot blood to some degree. The clot, however, is of generally poor quality.

Beryllium and barium exhibit some toxicity to living systems, and therefore should be used on humans and other mammals with caution. Barium could be considered for life saving hemostasis where it is only used once, as it is not as toxic as beryllium.

The alkaline earth oxides and peroxides of choice would be magnesium, calcium and strontium. However, the oxides of these three metals show relatively poor hemostasis as they tend to float on blood, forming a thin clot between the interface of the blood and oxide powder.

This inhibits further absorbance of blood into the oxide powder and the clot is very weak, causing it to be ruptured by blood pressure.

They also generate heat when put in contact with water. Strontium oxide tends to combine with blood better than MgO or CaO, producing some hemostasis. The peroxides of Mg, Ca and Sr are candidates for use in hemostasis. Zinc peroxide ZnO2 , although not an alkaline earth oxide, has some hemostatic activity.

All four of these peroxides as dry powders tend to be absorbed and interact with mammalian blood producing a clot suitable for hemostasis in humans. BaCl2, SrCl2. These alkaline earth ferrates are practically insoluble in water, and may be removed by filtration or centrifugation. The product is then washed repeatedly with water in order to remove the unwanted cations e.

For strontium ferrate production, the molar ratio of Sr to Fe can be from 0. A preferred range of molar ratio of Sr to Fe is from 1 :1 to 3. In one embodiment, the reactants are heated together at a temperature greater than about 0C for a period of time ranging from several minutes to several hours. In one embodiment, the reactants are heated together at a temperature greater than about 0C for about 15 hours.

In a further embodiment, the reaction takes place between 0C and 0C for between about 1 hour to 7 hours or more. In one embodiment, the reactants are heated at about 0C for about 3 hours. Tn a still further embodiment, the reactants are heated at about 0C for about 30 minutes. Tn yet a further embodiment, the reactants are heated at about 0C for between about 15 minutes and about 30 minutes.

In an exemplified embodiment, a method of the invention for producing barium ferrate involves intimately mixing about 9. The resulting barium ferrate product is of high purity. In one embodiment, the molar ratio of the Ba:Fe used in the reaction mixture is about Barium ferrate may be similarly produced from barium peroxide BaO2 , preferably wherein the ratio of Ba.

Fe used in the reaction mixture is about 1 :1 and the temperature and time regimes are similar to that used with barium oxide. Impurities of the reactions consist of un-reacted hematite and barium ferrite BaFeO2. Strontium ferrate may be produced in the same manner as barium ferrate described herein. It has been observed that the use of strontium peroxide as a reactant results in a better yield.

In an exemplified embodiment, an intimate mixture of about 1. In another embodiment, an excess of strontium peroxide or strontium oxide in relation to the Fe; i. The mixture of reactants wherein strontium is in molar excess compared to iron produces a composition with excellent hemostatic properties, including excellent clot strength and adhesion and rapid clotting time. In another embodiment, magnetite Fe3O4 may be used in place of Fe2O3 as an iron oxide source in the methods of the present invention.

Tn one embodiment, the Ba:Fe or SnFe molar ratio in the reactant mixture is about 1 The subject invention also concerns methods for producing alkaline earth ferrates, such as barium ferrate and strontium ferrate, using alkaline earth nitrates. The use of alkaline earth nitrates as oxidants to produce alkaline earth ferrates is not taught or suggested in the literature.

In one embodiment, a yield of calcium ferrate is obtained by heating a mixture of 1. Heating was performed at about 0C for about 30 minutes. Reactions using magnesium nitrate have not been successful. In one embodiment, about 1. When about 4. Magnetite Fe3O4 can also be used as an iron oxide source if the Fe:Ba ratios are about the same. In a still further embodiment, the reactants are heated at about 0C for about 30 minutes. In yet a further embodiment, the reactants are heated at about 0C for between about 15 minutes and about 30 minutes.

Intimate mixing of the nitrate reaction constituents is not as critical as that of the peroxide reaction, since the alkaline earth nitrates melt and combine with the iron oxide to form a slurry at a temperature lower than that of the ferrate formation reaction.

The subject invention also concerns methods that provide for a more rapid reaction for producing alkaline earth ferrates, such as strontium and barium ferrate. In one embodiment, the carbon is in the form of activated carbon. In one embodiment, about 0. The product resulting from the reaction has significant strontium ferrate Sr2FeO4 content. This reaction also works well with barium peroxide when weights are adjusted, but results are poor with calcium and magnesium peroxides.

The strontium reaction product exhibits good blood clotting properties. The subject invention also concerns the compositions produced using these methods. The compositions produced can be used as hemostatic and wound healing agents. Again, because of the toxicity of barium, the strontium reactions are preferable for production of hemostat agents.

Calcium and magnesium peroxides are not successfully used in this reaction, and clot blood no better than CaO2 and MgO2 alone. In one embodiment, the reaction takes place between 0C and 0C, for between about 1 hour to 7 hours or more, hi a further embodiment, the reactants are heated at about 0C for about 3 hours.

Tn a still further embodiment, the reactants are heated at about 0C for about 30 minutes, hi yet a further embodiment, the reactants are heated at about 0C for between about 15 minutes and about 30 minutes. Methods of the present invention can optionally include reaction with carbon powder wherein the reaction mixture is then ignited. The mixture is then ignited with a flame or other heat source.

The manganese oxides which may be utilized for hemostat synthesis include the following: MnO - natural manganosite Mn2O3 - natural braunite Mn3 O4 - natural hausmannite MnO2 - natural pyrolusite Some examples of manganese oxide and strontium peroxide blood clotting compositions produced according to the present invention are described in Examples herein.

These compositions can be produced by heating mixtures of metallic oxides and SrO2, or by using the carbon induced spontaneous reaction. In a further embodiment, the reaction takes place between 0C and 0C, for between about 1 hour to 7 hours or more. The mixture is ignited with a flame or other heat source.

Molybdenum oxide MoO3, natural molybdite , and tungsten oxide WO3, natural wolframite , may also have value as hemostats and wound healing agents or Molybite and tungsten oxides in lower oxidation states. Some examples of hemostatic compositions produced using metallic oxides are described in Examples 7 and 8 herein. On testing as hemostats, Al, Mg and Si are very poor blood clotters. Titanium oxide is a surprisingly fair clotter. Copper oxide yields a poor clotter, as it tends to react with the blood to form an interface barrier and not be absorbed.

Zinc oxide performs about the same as copper oxide. Zinc peroxide 1. Indeed, the existence of tetravalent cobalt is described as "resonance between the trivalent and the tetravalent cobalt atoms, and this must be favored by the presence of the peroxide group" Sidgwick, The compounds formed as products are very complex in these high temperature reactions.

Most of the information available concerns the ferrates and per manganates, but even that is very sparse when dealing with thermal fusion reactions. A temperature of about 0C can be used in the methods of the present invention. The decomposition temperature of strontium peroxide is 0C and it is here that the solid state reactions occur Vol'nov, Testing of the reaction products produced by the methods of the present invention is performed on fresh human blood or EDTA preserved porcine blood.

In one embodiment, three to four milliliters of blood is placed on a smooth plastic surface and the product applied to the blood drop, with the results observed over the next few minutes.

All of the hemostatic compounds and compositions produced by the methods described herein may be mixed with various hydrophilic resins, polymers and hydrogels in order to extend their blood clotting capabilities, such as those described in, for example, U. Patent Nos. Compositions of the invention comprising an alkaline earth ferrate of the invention can also comprise one or more cross-linked ionic hydrophilic polymers.

Polymers contemplated within the scope of the invention include, but are not limited to, carboxyvinyl polymer such as polymethacrylic acid, and, biodegradable crosslinked sodium carboxymethylcellulose or similar derivatives, biodegradable crosslinked starches for example, LYSORB, Archer Daniels Midland Corporation, Decatur, IL , guar gums, Arabic gums, karaya and other natural gums.

Polyacrylic acid polymer comprises the structure: The salt form of a polyacrylic acid polymer comprises the structure where M is a metal ion or other suitable ion : The salt form of polymers of the invention, such as polyacrylic acid, can be prepared from any suitable metal ion including, but not limited to, sodium, lithium, potassium, and calcium.

Ammonium and triethanolamine salts of polyacrylate are also contemplated within the scope of the invention. In one embodiment, a polyacrylic acid is provided as sodium polyacrylate. In a specific embodiment, the sodium polyacrylic acid is that form described for CAS registration number In one embodiment, cross-linked ionic polymers used in a composition of the invention are super absorbing polymers e.

Anak daun berbentuk lonjong dengan panjang sekitar sepuluh hingga dua pulu lima millimeter dan biasanya anak daun berjumlah antara sepuluh hingga dua pulu pasang.

Mudah bukan mencarinya, maka akan direkomendasikan menggunakan tumbuhan tersebut menjadi obat penyakit sipilis alami. Tentang Obat Sipilis Antibiotik Terampuh - Selain menggunakan khasiat tumbuhan yang dengan mudah kita temukan tersebut obat penyakit sipilis alami lainnya adalah adalah pencampuran antara beberapa tanaman rumah. Lalu bagimana cara mengolahnya agar dapat menjadi obat? Caranya cukup mudah ambil secukupnya beberapa tanaman rumah tersebut, kemudian setelah itu anda tumbuk sampai benar benar halus.

Setelah anda tumbuk sampai halus langkah selanjutnya adalah anda pisahkan ampas hasil tumbukan dengan sarinya. Nah hasil sari dari tumbukan tersebut dapat langsung diminum oleh kaum pria. Ramuan tradisional seperti ini selain dapat menjadi obat penyakit sipilis alami juga tentu akan aman apabila sering di konsumsi dan aman untuk di konsumsi secara rutin. Untuk melakukan peracikan sendiri memang sangat membuat anda repot. Selain sulit untuk mencari bahan bahannya karena biasanya tumbuh atau berada di tempat tempat tersentu.

Proses peracikannya pun memakan waktu. Apabila anda tidak ingin susah atau ingin yang simple anda dapat membeli bahan bahan alami yang sudah menjadi obat atau yang biasa kita kenal sebagai obat herbal.

Karena obat penyakit sipilis alami yang sudah berbentuk obat sudah sangat banyak beredar tentulah anda harus dapat memilih obat mana yang dapat di percaya dan memberikan manffat yang besar terhadap kesembuhan penyakit anda. Jangan malu untuk bertanya kepada penjual obat herbal tersebut, karena apabila anda salah dalam memilih obat herbal penyakit anda tidak akan sembuh.